Antazol Plus

Description

Medicine Overview of Antazol Plus 2.6mg+0.0325mg/spray Nasal Spray
Indication
Allergic rhinitis accompanied by nasal congestion
Adult Dose
Adults (including the elderly): One spray each nostril four times daily.
Child Dose
Children: One spray each nostril four times daily.
Contraindication
Contraindicated in patients with a known hypersensitivity to any ingredients of the preparation.
Mode of Action
Sodium Cromoglycate inhibits degranulation of mast cells and therefore suppresses the release of histamine, leukotrienes and slow-reacting substance of anaphylaxis. Xylometazoline is a direct-acting sympathomimetic which has a vasoconstrictor effect by reducing swelling and congestion when applied to mucous membranes.
Precaution
The prolonged use or abuse of decongestants in general may lead to rebound congestion or drug induced rhinitis.
Side Effect
No serious side effects have been reported. Occasional irritation of the nasal mucosa may occur during the first day of use. In rare cases with Sodium Cromoglicate solutions alone wheezing and tightness of the chest has been reported. Because a lower dose of Xylometazoline is employed in this preparation it causes mild side effects such as nasal irritation, dryness of the nose, sneezing, headache, insomnia, drowsiness and palpitations.
Interaction
Xylometazoline hydrochloride….Increased heart rate or BP with sibutramine. Potentially Fatal: Hypertensive crisis with MAOIs.